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[Preprint]. 2026 Apr 1:2026.03.30.26349798. [Version 1] doi: 10.64898/2026.03.30.26349798

Table 3.

Joint display of quantitative (survey) and qualitative (interview) findings

Finding from quantitative analysis [surveys] Themes from qualitative analysis and illustrative quotes [interviews] Integration of quantitative and qualitative findings
BESD domain: Thinking and Feeling
Adolescents were more willing to receive a new TB vaccine than adults. (Source: Table 2) Caregivers and adults said they wanted more information on why the vaccine would be offered to them and how it works.
Quote: “I am not saying I would not choose it, I do not know its behavior. I do not know what it does after application, how it reacts in the person’s body after application.”-Adult
Surveys showed adults and caregivers were less willing to be vaccinated; interviews suggested this hesitancy was due to a need for more information on the vaccine.
Participants with a higher knowledge of TB were more willing to receive a new TB vaccine than those with lower knowledge. (Source: Table 2) Participants had a general understanding of TB as an illness (i.e. symptoms), but various misconceptions around transmission highlighted some knowledge gaps. Some cited health behaviors (i.e. unprotected sex or alcohol use) as leading to Mtb infection.
Quote: “as I understand it, I can transmit it to another person when, for example, I cough without covering my mouth, and my saliva passes to the other person” - Adult
Survey data demonstrated statistical associations between knowledge of TB and willingness to vaccinate; interviews revealed the types of misconceptions held about TB.
Participants reporting personal experience with TB (a friend or family member with the disease) were more willing to receive a new TB vaccine than those who did not. (Source: Table 2) Participants who knew someone with TB expressed the importance of preventing TB through all means (e.g., treatment of Mtb infection, regular health screenings). Vaccination was seen as another method of prevention that would be important for protecting themselves and other family members, especially young children.
Quote: “The vaccine will prevent the disease I have and yes, I will feel good about my health.” -Adolescent with TB
Surveys demonstrated an association between personal experience with TB and willingness to receive a vaccine. Interviews showed that participants with experience of TB felt that all prevention methods were important but especially saw value in a vaccine to keep the community safe. There was great emphasis on making sure other family members (particularly young children) were safe from Mtb infection, which was explained in in-depth interviews but not explored in the survey.
Not assessed. Only a few participants expressed true doubt or hesitancy. Concerns focused on vaccine development and testing in a location not deemed ‘technologically advanced’. -
BESD domain: Social Processes
Most trusted sources of information were healthcare providers, government agencies; participants had relatively little trust in information from social networking sites. (Source: Supplemental Table 1) Information sources included advertisements, social media, and outreach workers. Many expressed distrust of messages via social platforms (i.e. WhatsApp).
Quote: “…but if I have any doubts, I should go to a health center and tell them that I heard that information on television, so I went there to find out if it was true, and then they’ll clarify it for me.” – Adult
Both surveys and interviews captured similar data on sources of trusted information: participants reported that messages from the health system were trusted and information coming from social networking platforms was not.
People most influencing a person’s decision to receive a vaccine were health providers/community health workers, themselves (the respondents), and local community leaders. (Source: Supplemental Table 2) Social influences are described as significant motivators. These include healthcare professionals, the neighborhood ‘secretary’, family, community leaders, and spouses.
Quote: “I chose these people because they know what they’re talking about, they can’t mislead me.” – Caregiver
Both surveys and interviews captured similar data on who influences vaccination decisions, showing a strong influence of other family members, healthcare providers, and community leaders.
BESD domain: Motivation
Participants who reported previous issues accessing vaccines were more willing to receive a new TB vaccine than those who did not. (Source: Table 2) Prior vaccination was reported as generally a positive experience, even if minor side effects were felt.
Quote: “When I vaccinated at school, I felt good because it was necessary for me to be vaccinated for the good of my health but nothing went wrong with me, I liked the vaccine” - Adult
Surveys showed that previous issues accessing vaccines made individuals more willing to receive a TB vaccine. This was discordant with interview data, in which a majority of respondents reported that previously receiving vaccines and having positive experiences with accessing and receiving them led to an interest in the new vaccine.
Most important factors cited in influencing vaccination decisions were whether the vaccine prevented disease and was deemed ‘important’. (Source: Supplemental Table 3) Participants felt that if they were assured the vaccine could prevent Mtb infection and keep them healthy, they would be willing to take it.
Quote: “so that you can be vaccinated and you’ll have a lot of health in your life…” - Adult
Both surveys and interviews showed that effectiveness of the vaccine in preventing Mtb infection/TB is an important factor in vaccination decisions. Survey data additionally suggested that participants also valued a healthcare professional’s evaluation of whether it was ‘important’ for their health.
BESD domain: Practical Issues
Not assessed. Locations like schools, clinics, and hospitals that serve as education centers were also seen as possible places of vaccine administration.
Quote: “The advantage of the school is that everything they teach there comes from the Ministry of Health, so I trust the school.“ - Adult
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