Table 2.

Anatomical interpretation of sex-specific shape modes describing distinct LV remodeling. Effects correspond to baseline +1 SD.

Mode & sex	General pattern	Effect of +1 SD (inner-distance / thickness / spatial notes)
Mode 1 (Female)	Septal–lateral contrast	Inner-distance decreases in septal/apical regions while relatively preserved in lateral/inferior walls; thickness remains largely unchanged.
Mode 2 (Female)	Apical–basal and regional variation	Inner-distance increases in lateral and anterior apical regions, while septal and inferior walls show decreases along most of the LV; mild overall thinning.
Mode 3 (Female)	Apex vs. remaining LV	Inner-distance increases at the apical tip, whereas most of the remaining LV walls exhibit decreased inner-distance; accompanied by mild thinning.
Mode 5 (Male)	Global septal-dominant remodeling	Smooth decrease in inner-distance across most walls, most pronounced in basal septal regions; thickness unchanged.
Mode 7 (Male)	Global gradient with focal patches	Broad gradient in inner-distance with focal effects in apical septum and basal lateral wall; thickness generally increases.
Mode 11 (Male)	Thickness-driven variation	Minimal net change in inner-distance; diffuse reduction in wall thickness.