Table 4.

Copy number estimates of the PHRs across the RPC cohort (n=4,187) and UK Biobank WGS cohort (n=490,374).

Cohort	Num. of PHRs	Num. of samples	%	XX	%	XY	%
RPC	<4	3	0.07%	0	0.00%	3	0.15%
	4	261	6.23%	126	5.93%	135	6.54%
	5	1,645	39.29%	828	39.00%	817	39.58%
	6	2,189	52.28%	1,127	53.09%	1,062	51.45%
	7	85	2.03%	39	1.84%	46	2.23%
	>7	4	0.10%	3	0.14%	1	0.05%
	Total	4,187	100.00%	2,123	100.00%	2,064	100.00%
RPC (Parents only)	<4	1	0.04%	0	0.00%	1	0.08%
	4	143	5.47%	67	5.14%	76	5.81%
	5	931	35.64%	453	34.74%	478	36.54%
	6	1,477	56.55%	755	57.90%	722	55.20%
	7	59	2.26%	28	2.15%	31	2.37%
	>7	1	0.04%	1	0.08%	0	0.00%
	Total	2,612	1	1,304	100.00%	1,308	100.00%
UK Biobank	<4	234	0.05%	128	0.05%	106	0.05%
	4	33,964	6.93%	18,195	6.84%	15,769	7.03%
	5	185,625	37.85%	100,601	37.82%	85,024	37.89%
	6	262,723	53.58%	142,803	53.69%	119,920	53.45%
	7	7,631	1.56%	4,164	1.57%	3,467	1.55%
	>7	197	0.04%	104	0.04%	93	0.04%
	Total	490,374	100.00%	265,995	100.00%	224,379	100.00%