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[Preprint]. 2026 Mar 27:2026.03.08.710242. [Version 2] doi: 10.64898/2026.03.08.710242

Key resources table

REAGENT or RESOURCE SOURCE IDENTIFIER
Oligonucleotides and Probes
DJ OligoMix - 5’ Biotin L LC Sciences, LLC Custom 100bp oligo paint corresponding to
CHM13 chr13:5424523–5770548
CenSat D14Z1/D22Z1 Cytocell LPE 014
Human whole chromosome paint (chr15) Applied Spectral Imaging FPRPR0167
45S rDNA probe Empire genomics RP11–450E20
Experimental models: Cell lines
CHM13 Magee-Womens Hospital (Pittsburgh)
IRB MWH-20–054
CHM13
HG002 Coriell Institute for Medical Research GM24385
GM03417 Coriell Institute for Medical Research GM03417
GM03786 Coriell Institute for Medical Research GM03786
GM04890 Coriell Institute for Medical Research GM04890
HG01204 Coriell Institute for Medical Research HG01204
HG00619 Coriell Institute for Medical Research HG00619
HG00620 Coriell Institute for Medical Research HG00620
HG01981 Coriell Institute for Medical Research HG01981
HG01890 Coriell Institute for Medical Research HG01890
HG01889 Coriell Institute for Medical Research HG01889
GM02752 Coriell Institute for Medical Research GM02752
GM20805 Coriell Institute for Medical Research GM20805
Software and algorithms
Bedtools (v2.31.1) Aaron R. Quinlan et al. https://bedtools.readthedocs.io/en/latest/
BWA-MEM (v0.7.17) Heng Li et al. https://github.com/lh3/bwa
compleasm (v0.2.7) Neng Huang et al. https://github.com/huangnengCSU/compleasm
GenomeScope (v2.0) Rhyker Ranallo-Benavidez et al. https://github.com/schatzlab/genomescope
IGV (v2.18.2) Robinson et al. https://igv.org/
mashmap (v3.1.1) Chirag Jain et al. https://github.com/marbl/MashMap
merqury (v1.4.1) Arang Rhie et al. https://github.com/marbl/merqury
meryl (v1.4.1) Arang Rhie et al. https://github.com/marbl/merqury
Minimap2 (v2.30) Heng Li https://lh3.github.io/minimap2/
ModDotPlot (v0.9.0) Sweeten et al. https://github.com/marbl/ModDotPlot
paftools Heng Li https://lh3.github.io/minimap2/
Picard (v3.3.0) https://github.com/lh3/bwa
Rustybam (v0.1.33) Mitchell R Vollger et al. https://www.vollgerlab.com/rustybam/
Samblaster (v0.1.26) Gregory G. Faust et al. https://github.com/GregoryFaust/samblaster
Samtools (v1.21) Heng Li et al. https://www.htslib.org/
scipy (v1.13.1) Virtanen, P., et al. https://scipy.org/
seqtk (v1.4) Heng Li https://github.com/lh3/seqtk
statsmodels (v0.14.5) Seabold and Skipper et al. https://www.statsmodels.org/stable/index.html
Verkko (v2.2.1) Dmitry Antipov et al. https://github.com/marbl/verkko
Yak (yak-0.1 (r56)) Heng Li https://github.com/lh3/yak