Table 2.
Contents of amino acid derivatives in mouse serum under different treatments (µmol/L).
| Items | Comparison of amino acid derivatives content | P-value | ||
|---|---|---|---|---|
| CON | PFOA | OBS | ||
| Gamma-Aminobutyric Acid (GABA) | 0.17±0.07 | 0.13±0.07 | 0.12±0.06 | 0.466 |
| Taurine (Tau) | 454.03±122.58 | 461.85±43.11 | 381.17±50.33 | 0.256 |
| Citrulline (Cit) | 54.50±7.15b | 71.08±11.14ab | 81.99±13.47a | 0.006 |
| Ornithine (Orn) | 58.48±11.68 | 71.07±23.07 | 55.48±9.83 | 0.298 |
| α-Aminoadipic Acid (AAA) | 10.99±2.58a | 6.20±0.80b | 4.86±1.55b | <0.001 |
| α-Aminobutyric Acid (AABA) | 4.38±0.81ab | 3.92±0.91b | 5.78±1.16a | 0.027 |
| α-Aminosuberic Acid (Asu) | 0.13±0.11b | 0.47±0.17a | 0.34±0.12a | 0.006 |
| Cystathionine (Cth) | 1.27±0.21 | 1.11±0.29 | 1.32±0.23 | 0.370 |
| Homocitrulline (Hcit) | 0.52±0.07b | 0.61±0.08b | 1.26±0.10a | <0.001 |
| Total Homocysteine (tHcy) | 4.14±0.68b | 8.44±1.45a | 4.09±1.39b | <0.001 |
| 1-Methylhistidine (1-MHis) | 4.40±0.86b | 7.13±1.26a | 5.39±0.64b | 0.002 |
| 3-Methylhistidine (3-MHis) | 6.49±1.10b | 8.80±1.68ab | 9.51±1.77a | 0.024 |
| Carnitine (Car) | 1.00±0.29 | 0.86±0.09 | 0.95±0.16 | 0.516 |
| Ethanolamine (Etn) | 15.75±2.08a | 13.25±1.32ab | 10.69±1.95b | 0.003 |
| Phosphoserine (P-Ser) | 0.13±0.04a | 0.03±0.03b | 0.10±0.05a | 0.005 |
| Hydroxylysine (Hylys) | 0.34±0.09 | 0.25±0.14 | 0.19±0.05 | 0.093 |
| Sarcosine (Sar) | 1.14±0.16b | 0.82±0.23b | 1.66±0.31a | <0.001 |
| Phosphoethanolamine (PEtn) | 4.24±2.26a | 1.20±0.35b | 3.83±1.03a | 0.012 |
| Hydroxyproline (Hyp) | 17.40±3.20a | 10.19±2.77b | 10.55±1.09b | 0.001 |
| β-Alanine (β-Ala) | 9.39±2.43a | 4.97±0.43b | 4.21±0.88b | <0.001 |
| Kynurenine (Kyn) | 0.57±0.14 | 0.48±0.09 | 0.58±0.12 | 0.356 |
| Anserine (Ans) | 1.22±0.23 | 1.1±0.24 | 1.18±0.22 | 0.696 |
In the same row, data with different small letter superscripts mean significant difference (P < 0.05), while with the same or no letter superscripts mean no significant difference (P > 0.05).