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. Author manuscript; available in PMC: 2026 Apr 10.
Published in final edited form as: Respir Physiol Neurobiol. 2022 Sep 26;307:103964. doi: 10.1016/j.resp.2022.103964

Table 3.

Recovery from mechanical hyperventilation, cough induced hyperventilation (CHV), and isocapnic coughing.

Compared to ventilator Compared to cough
Condition Mean ± SE Δ (%) Test p -value Δ (%) Test p -value
Apnea Duration (s)
 Ventilator 40 ± 6 - - - - - -
 CHV 17 ± 3 −56 T 0.017 ♦ - - -
 Isocapnia 6 ± 2 −86 M 0.002 ¤¤ −68 W 0.004 ##
Hypopnea Duration (s)
 Ventilator 45 ± 8 - - - - - -
 CHV 63 ± 12 42 T 0.213 - - -
 Isocapnia 16 ± 5 −64 M 0.039 ¤ −75 W 0.006 ##

Welch’s t-test (T)

♦♦♦ =

p < 0.001,

♦♦ =

p < 0.01,

♦ =

p < 0.05

Mann-Whitney test (M)

¤¤¤ =

p < 0.001,

¤¤ =

p < 0.01,

¤ =

p < 0.05

Wilcoxon singed-rank test (W)

### =

p < 0.001,

## =

p < 0.01,

# =

p < 0.05

CHV/Isocapnia n = 12, Ventilator n = 5.