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. 2002 May;40(5):1681–1686. doi: 10.1128/JCM.40.5.1681-1686.2002

TABLE 2.

Antimicrobial concentration ranges and breakpoints used in AST

Microorganism(s) and antimicrobial agent MIC (μg/ml) range determined by method
Breakpointa (μg/ml)
VITEK 2 Referenceb Susceptible Resistant
Staphylococcus spp.
    Clindamycin 0.25-8 0.015-32 0.5 4
    Erythromycin 0.25-8 0.015-32 0.5 8
    Gentamicin 0.5-16 0.03-64 4 16
    Norfloxacin 0.25-16 0.03-16 2 16
    Oxacillin 0.5-8 0.03-64 2 (0.25c) 4 (0.5c)
    Rifampin 0.5-32 0.015-32 1 4
    Teicoplanin 0.5-32 0.015-16 8 32
    Vancomicin 1-32 0.05-16 4 32
Enterococcus spp.
    Ampicillin 2-32 0.015-32 8 16
    Teicoplanin 0.5-16 0.015-16 8 32
    Vancomycin 1-16 0.015-16 4 32
    HC Gentamicin 120 500 500
    HC Streptomycin 200 2,000 2,000
S. agalactiae
    Ampicillin 0.25-32 0.015-32 0.25
    Clindamycin 0.25-8 0.015-32 0.25 1
    Erythromycin 0.25-8 0.015-32 0.25 1
    Teicoplanin 0.5-16 0.015-16
    Tetracycline 1-16 0.03-16 2 8
    Vancomycin 1-16 0.015-16 1
S. pneumoniae
    Penicillin 0.06-2 0.015-32 0.06 2
    Cefotaxime 0.06-4 0.12-32 0.5 2
    Erythromycin 0.06-1 0.015-32 0.25 1
    Ofloxacin 1-8 0.03-16 2 8
a

Breakpoints as given in reference 14.\

b

Agar dilution.\

c

Breakpoint for CNS.