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. 2026 Feb 28;26:184. doi: 10.1186/s12880-026-02247-w

Table 4.

99TCm-DX Lymphoscintigraphic manifestations in SLE and RA Patients with Lymphatic System Involvement

99TCm-DX Lymphoscintigraphic manifestations SLE with lymphatic system involvement (n = 25) RA with lymphatic system involvement (n = 18) P value
No visualization or visualization at 1 h of the left jugular venous angle 0(0.0) 12(66.7) 0.000
Continuous visualization of bilateral jugular venous angles 1(4.0) 0(0.0) 1.000
Continuous visualization of left jugular venous angle 23(92.0) 6(33.3) 0.000
Continuous visualization of the right venous angle, no visualization of the left venous angle 1(4.0) 0(0.0) 1.000
Dilation and persistent visualization of the thoracic segment of thoracic duct 2(8.0) 1(5.6) 1.000
Radiographic contrast reflux of left subclavian trunk 2(8.0) 0(0.0) 0.502
Radiographic contrast reflux of bronchial mediastinal trunk 1(4.0) 0(0.0) 1.000
Dilation of iliac lymphatic vessels and lumbar trunks 1(4.0) 0(0.0) 1.000
Limb lymphedema (unilateral/bilateral, upper/lower limb) 4(16.0) 14(77.8) 0.000
Unilateral upper limb lymphedema 0(0.0) 1(5.6) 0.419
No lymphatic reflux in the edematous upper limb; slow lymphatic return in the contralateral upper limb 0(0.0) 1(5.6) 0.419
Bilateral upper limb lymphedema 0(0.0) 3(16.7) 0.066
No lymphatic reflux in both upper limbs 0(0.0) 2(11.1) 0.169
Slow lymphatic reflux in both upper limbs 0(0.0) 1(5.6) 0.419
Unilateral lower limb lymphedema 3(12.0) 6(33.3) 0.133
No lymphatic reflux in the edematous lower limb; slow lymphatic return in the contralateral lower limb 1(4.0) 2(11.1) 0.562
No lymphatic reflux in the edematous lower limb; normal lymphatic reflux in the contralateral lower limb 0(0.0) 3(16.7) 0.066
Slow lymphatic return in the edematous lower limb; normal lymphatic reflux in the contralateral lower limb 2(8.0) 1(5.6) 1.000
Bilateral lower limb lymphedema 1(4.0) 4(22.2) 0.144
No lymphatic reflux in the edematous lower limb; slow lymphatic return in the contralateral lower limb 0(0.0) 1(5.6) 0.419
Slow lymphatic reflux in both lower limbs 1(4.0) 3(16.7) 0.293
No lymphedema in the both lower limbs, slow lymphatic return 14(56.0) 1(5.6) 0.001
chylous effusion (pleural/peritoneal/pericardial) 22(88.0) 4(22.2) 0.000
Chylous hydrothorax 12(48.0) 2(11.1) 0.011
Chylous ascites 1(4.0) 2(11.1) 0.562
Chylous pleural and peritoneal effusions 6(24.0) 0(0.0) 0.032
Chylopericardium 2(8.0) 0(0.0) 0.502
Chylopericardium and chylous hydrothorax 1(4.0) 0(0.0) 1.000

The values with statistical significance (P < 0.05) are displayed in bold