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. 2026 Apr 6;24:160. doi: 10.1186/s12957-026-04327-1

Table 4.

Leave-one-out sensitivity analyses for key outcomes, showing pooled effect estimates, P-values, and between-study heterogeneity (I²) before and after exclusion of the study that yielded the lowest heterogeneity for each endpoint

Outcome Effect estimates (before) P-value (before) I²% (before) Study removed in leave-one-out Effect estimates (after) P-value (after) I²% (after)
Incidence of postoperative seroma RR 0.36 < 0.00001 65% Awad 2019 RR 0.43 < 0.00001 15%
Need for seroma aspiration RR 0.29 < 0.00001 30% Awad 2019 RR 0.34 < 0.00001 0%
Number of seroma aspirations MD − 1.03 0.0003 95% Khater 2015 MD − 0.62 0.01 94%
Total drainage volume (mL) MD − 214.44 0.03 98% Awad 2019 MD − 167.43 0.02 89%
Duration to drain removal (days) MD − 2.01 0.22 99% Awad 2019 MD − 0.96 0.01 56%