Table 1. Muscle weights of mice injected with ACVR2B/Fc.

		Muscle weight, mg
Mice	No.	Pectoralis	Triceps	Quadriceps	Gastrocnemius
WT
+ PBS	(n = 10)	46.3 ± 1.2	70.9 ± 1.8	142.1 ± 2.9	99.1 ± 1.9
+ ACVR2B/Fc
10 mg/kg, 1 wk	(n = 6)	57.8 ± 2.8*	89.0 ± 4.5*	166.7 ± 6.6*	115.0 ± 5.0†
10 mg/kg, 2 wk	(n = 10)	68.1 ± 1.8‡	96.3 ± 2.3‡	185.4 ± 4.1‡	124.6 ± 3.1‡
10 mg/kg, 3 wk	(n = 10)	64.0 ± 1.7‡	96.4 ± 2.2‡	182.2 ± 5.1‡	121.4 ± 2.9‡
10 mg/kg, 4 wk	(n = 10)	63.8 ± 1.5‡	99.5 ± 2.5‡	188.0 ± 4.8‡	131.6 ± 2.8‡
30 mg/kg, 2 wk	(n = 6)	67.2 ± 3.8*	103.7 ± 3.3‡	191.7 ± 7.4§	125.8 ± 5.0*
50 mg/kg, 2 wk	(n = 7)	71.0 ± 1.2‡	114.4 ± 2.9‡	204.7 ± 4.5‡	138.1 ± 3.5‡
Mstn-/-
+ PBS	(n = 10)	104.6 ± 3.2	154.9 ± 4.1	267.0 ± 7.6	177.2 ± 5.9
+ ACVR2B/Fc
10 mg/kg, 4 wk	(n = 10)	129.3 ± 3.6¶	194.7 ± 5.3¶	306.7 ± 7.9∥	214.8 ± 5.4**

^*, P < 0.01 vs. WT + PBS

^†, P < 0.05 vs. WT + PBS

^‡, P < 0.0001 vs. WT + PBS

^§, P < 0.001 vs. WT + PBS

^¶, P < 0.0001 vs. Mstn^-/- + PBS

^∥, P < 0.01 vs. Mstn^-/- + PBS

^**, P < 0.001 vs. Mstn^-/- + PBS