Skip to main content
. 2005 Dec 5;102(50):18093–18098. doi: 10.1073/pnas.0509311102

Fig. 1.

Fig. 1.

Amplification and analysis of expressed Ig V regions from single EBV+ memory B cells. (A) Amplification of Ig V regions from 11 single cells. Each cell should result in the 400-bp (arrow) amplification of one heavy chain and one light chain. (The asterisks denote cells that were also EBER1-positive.) (B) Sequence alignment of an amplified EBV+ VH gene to its germ-line counterpart from AIM patient 4. The codon numbering is according to chothia. The location of the CDRs is indicated by solid lines above the sequences. R mutations are in uppercase, and S mutations are in lowercase. SHM hotspots are in bold. The location of the forward primer is underlined.