TABLE 3.

Grouping of sheep scrapie samples based on transmissibility to mice and relative PK resistance of PrP^Sc

Sheep	PK resistancea (Sheep PrPSc)	Transmissibility to ICR mice (mean ± SD [day])	PK resistanceb (Mouse PrPSc)
Group 1
KH2	H	Yes ( 417 ± 29)	H
KU	H	Yes ( 394 ± 67)	H
SB	H	Yes ( 451 ± 39)	NDc
Y2	H	Yes ( 418 ± 42)	ND
Y5	H	Yes ( 427 ± 15)	H
G1	H	Yes ( 386 ± 20)	ND
Group 2
S1	H	No	NAd
S2	H	No	NA
S3	H	No	NA
Group 3
A1	L	Yes ( 229 ± 12)	L
B3	L	Yes ( 236 ± 14)	L

^aH indicates PrP^Sc that is resistant to a treatment with PK (40 μg/ml) for 2 h, while L indicates PrP^Sc that is sensitive to the same treatment.

^bH indicates PrP^Sc that is resistant to a treatment with PK (200 μg/ml) for 1 h, while L indicates PrP^Sc that is sensitive to the same treatment.

^cND, not determined.

^dNA, not available.