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The translocated effector proteins NleC and NleD are not required for persistence of EHEC O157:H7 in lambs. Colonization is indicated by viable bacterial counts from fecal samples taken at different time points postinfection. Lambs were infected with ca. 109 CFU of the EHEC O157:H7 85-170 parental strain (closed circles), nleC mutant (open squares), or nleD mutant (open circles). Error bars show standard deviations.
