Table 3:

Recommended Cancer Screening in Liver Transplant Candidates

	Screening Test	Screening interval
Hepatocellular carcinoma	Liver ultrasound and alpha fetoprotein If poor liver visualization is noted on ultrasound a liver MRI or CT should be conducted for surveillance If cross-sectional imaging is planned for other purposes, then it should be protocoled to screen for HCC	Every 6 months
Colorectal Cancer	Average risk patients ≥45 years old should undergo screening using colonoscopy or Stool DNA-FIT testing Higher than average risk patients should be screened using colonoscopy	High quality colonoscopy should be conducted with the last 10 years. More frequent intervals per guidelines based on polyp history, family history, or with the presence of any hereditary syndromes Stool based DNA-FIT testing should be completed every 1-3 years
Breast Cancer	Female candidates ≥ 40 years old should undergo mammography In candidates unable to undergo mammography, alternate tests such as breast ultrasound or MRI could be considered	Screening should be conducted on a biennial basis
Cervical Cancer	Female candidates ≥ 21 years old should undergo screening with cytology and high-risk human papillomavirus testing	Screening should be conducted every 3 years in average risk individuals up to 49 years of age Screening should be conducted every 5 years in average risk individuals ≥ 50 years of age
Lung Cancer	Candidates aged ≥ 50 years old with a history of 20 pack year smoking history should undergo low dose CT chest. Screening should be discontinued in patients who have not smoked in 15 years.	Screening should be conducted annually
Prostate Cancer	Prostate cancer screening should be conducted in male candidates ≥ 50 years of age	Annual prostate specific antigen testing

Abbreviations: MRI: Magnetic Resonance Imaging, CT: Computed Tomography, DNA-FIT: Fecal Immunochemical Test