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. Author manuscript; available in PMC: 2026 Apr 13.
Published before final editing as: Hepatology. 2025 Dec 17:10.1097/HEP.0000000000001644. doi: 10.1097/HEP.0000000000001644

Table 7:

Future Directions in the Liver Transplant Evaluation

Transplant Selection Can evaluation for LT be made a community-health-based process?
Should a quality-of-life assessment be included in candidate selection?
Malignancy Should routine downstaging be performed in HCC looking at the impact of immunotherapy?
When should transplant be done for non-hepatic malignancy?
Is there a role for transplant in treating primary or secondary cancers with a goal of life-extension rather than cure? How much lifeextension justifies the transplantation?
Cardiopulmonary
Testing
Are there advanced echocardiographic parameters to better define cirrhotic cardiomyopathy and its impact on transplant candidate selection?
Physical Function Can we better understand the impact of interventions on optimizing physical function in decompensated patients in the pre-transplant period?
Psychosocial Assessment Can prospective studies better determine what constitutes psychosocial unsuitability?
Contraindications Does high BMI continue to have an outcome impact in the era of advanced bariatric management?
Bone Health Do bisphosphonates have an impact on bone health outside of the pathology of primary biliary cholangitis?
Multiple Organ Transplant What are the appropriate medical eligibility criteria for choosing patients and determining allocation for heart-liver and lung-liver transplants?