Table 7:
Future Directions in the Liver Transplant Evaluation
| Transplant Selection | Can evaluation for LT be made a community-health-based process? |
| Should a quality-of-life assessment be included in candidate selection? | |
| Malignancy | Should routine downstaging be performed in HCC looking at the impact of immunotherapy? |
| When should transplant be done for non-hepatic malignancy? | |
| Is there a role for transplant in treating primary or secondary cancers with a goal of life-extension rather than cure? How much lifeextension justifies the transplantation? | |
|
Cardiopulmonary
Testing |
Are there advanced echocardiographic parameters to better define cirrhotic cardiomyopathy and its impact on transplant candidate selection? |
| Physical Function | Can we better understand the impact of interventions on optimizing physical function in decompensated patients in the pre-transplant period? |
| Psychosocial Assessment | Can prospective studies better determine what constitutes psychosocial unsuitability? |
| Contraindications | Does high BMI continue to have an outcome impact in the era of advanced bariatric management? |
| Bone Health | Do bisphosphonates have an impact on bone health outside of the pathology of primary biliary cholangitis? |
| Multiple Organ Transplant | What are the appropriate medical eligibility criteria for choosing patients and determining allocation for heart-liver and lung-liver transplants? |