TABLE 1.

Gonococcal association with and intracellular survival within primary human cervical epithelial cells^a

N. gonorrhoeae strain 1291	Association	Invasion (T = 0)	Invasion + 1 h (T = 1)	Invasion + 2 h (T = 2)
WT	27.81 (2.66)	2.80 (0.12)	2.80 (0.25)	6.37 (0.33)
laz	18.04 (0.69)	1.36 (0.25)	0.94 (0.10)	0.44 (0.08)

^aValues given are the mean (variance) of the percent total association or invasion as a function of the original inoculum, determined from the number of CFU formed upon plating of the cervical cell lysates. Data were obtained from three trials performed in triplicate. At each of the four time points, there was a statistically significant difference in the mean percent survival of the laz mutant relative to N. gonorrhoeae strain 1291 wild type (WT) (P ≤ 0.05, as determined using a Kruskal-Wallis nonparametric analysis of variance). T, time.