TABLE 2.

Numbers of TNF-α⁺ and IL-10⁺ cells and relative contributions of the CD68⁺ population to the production of these cytokines in lesions from patients with CL and ML

Clinical form	TNF-α production				IL-10 production
	No. of TNF-α+ cellsa		% Contribution of CD68+ cellsb	% Commitment of CD68+ cellsc	No. of IL-10+ cellsa		% Contribution of CD68+ cellsb	% Commitment of CD68+ cellsc
	Total	CD68+			Total	CD68+
CL (n = 14)	1,144 ± 691	909 ± 547	78 ± 12	65 ± 21	2,025 ± 785	1,267 ± 598	62 ± 13	79 ± 16
ML (n = 7)	1,354 ± 993	1,148 ± 937	80 ± 12	56 ± 23	2,468 ± 1,597	1,148 ± 1,158	53 ± 17	91 ± 4d

^aCounted based on expression of specific fluorescent markers for TNF-α or IL-10 either alone or together with CD68, as described in Materials and Methods.

^bCalculated as the percentage of CD68⁺ cells expressing the cytokine in relation to the total expression of the cytokine.

^cCalculated as the percentage of CD68⁺ cells expressing the cytokine in relation to total CD68⁺ cells.

^dStatistically significantly different from the value for CL (P < 0.05).