TABLE 3.

Expression of iNOS and granzyme A in lesions from patients with CL and ML

Clinical form	iNOS expression		Granzyme A expression
	No. of iNOS+ cellsa	% iNOS+ cells	No. of granzyme A+ cellsa		% Contribution of CD8+ cellsb	% Commitment of CD8+ cellsc
			Total	CD8+
CL (n = 9)	1,274 ± 230	87 ± 6	924 ± 466	687 ± 391	70 ± 21	58 ± 13
ML (n = 7)	1,159 ± 231	64 ± 19d	1,562 ± 610e	950 ± 587	56 ± 14d	74 ± 17e

^aCounted based on expression of specific fluorescence for either granzyme A or iNOS alone or granzyme A and CD8, as described in Materials and Methods.

^bCalculated as the percentage of CD8⁺ cells expressing granzyme A in relation to total granzyme A expression.

^cCalculated as the percentage of CD8⁺ cells expressing granzyme A in relation to total CD8⁺ cells.

^dSignificantly lower than value for CL (P < 0.05).

^eSignificantly higher than value for CL (P < 0.05).