FIG. 5.
Proliferative response to overlapping peptides MSP3-a, -b, -c, and -d. The box plots show the 5th, 25th, 50th, 75th, and 95th percentiles for the distribution of stimulation indices (S.I.) induced by the various peptides in each immunization group. SI were calculated by determining the ratio of peptide-stimulated PBMC to unstimulated PBMC in cpm after the second injection. Each culture was performed with six replicates. Stimulation with peptides MSP3-a, -b, -c, and -d was performed parallel to MSP3-LSP stimulation for comparison (Fig. 4).