. 2005 Dec;73(12):8256–8265. doi: 10.1128/IAI.73.12.8256-8265.2005

TABLE 5.

Serum MCP-specific and CRM197-specific IgG subclass GMC and percentage of each subclass in total IgG concentration

Parameter for group	MCP				CRM197
	Intramuscular naive	Nasal		Total nasal^c	Intramuscular naive	Nasal		Total nasal^c
	Intramuscular naive	Naive^a	Preimmunized^b	Total nasal^c	Intramuscular naive	Naive^a	Preimmunized^b	Total nasal^c
No.	6	13	17	30	6	13	17	30
GMC (μg/ml)
IgG1	4.3	3.3	5.6	4.4	66.4	19.4	30.6	25.1
IgG2	10	14.7	16.5	15.7	21.7	23.3	22.6	22.9
IgG3	0.56	0.48	1.0	0.7	0.4	0.29	0.23	0.25
IgG4	1.1	1.4	1.2	1.3	92.0	43.3	39.1	40.9
% of total IgG^d
IgG1	27	17	23	20	37	22	33	28
IgG2	63	74	68	71	12	27	24	26
IgG3	4	2	4	3	0.2	0.3	0.2	0.3
IgG4	7	7	5	6	51	50	42	46
Between-subclass differences^e
IgG1 vs IgG2	NS	***	*	***	NS	NS	NS	NS
IgG1 vs IgG3	*	***	***	***	*	***	***	***
IgG1 vs IgG4	NS	NS	***	***	NS	NS	NS	NS
IgG2 vs IgG3	***	***	***	***	NS	***	***	***
IgG2 vs IgG4	**	***	***	***	NS	NS	NS	NS
IgG3 vs IgG4	NS	*	NS	NS	**	***	***	***

Groups 1 and 3.

Group 2.

Groups 1, 2, and 3.

May not total 100% due to rounding.

Bonferroni's multiple-comparison test: NS, not significant (P > 0.05); *, P < 0.05; **, P < 0.01; ***, P < 0.001.