FIG. 6.

Peptide C8 drives class switching of the antibody response to MSP1₁₉, GST, and BSA to IgG2b. Ratios of midpoint titers of IgG2b to IgG1 antibodies to (a) MSP11₁₉ (b) GST, and (c) BSA in the sera of C57BL/6 mice (four per group) immunized with (a, b) MSP1₁₉-GST, MSP1₁₉-GST conjugated with peptide C8 (C8-MSP1₁₉-GST), MSP1₁₉-GST conjugated with an irrelevant peptide (L-MS1₁₉-GST), (c) BSA alone, BSA conjugated to peptide L (L-BSA), or BSA conjugated to C8 (C8-BSA). Each bar represents the IgG2b/IgG1 ratio for serum from one mouse. * indicates a serum where the ratio was 1.0.