TABLE 3.
Protection against B. melitensis or B. ovis in mice immunized with the 27-aa peptide
| Treatment group (n = 8) | Log10aB. melitensis organisms in spleen | Log units of protection in spleen | Log10aB. ovis organisms in spleen | Log units of protection in spleen |
|---|---|---|---|---|
| PBS | 5.10 ± 0.38 | 4.77 ± 0.49 | ||
| Omp3148-74 | 3.95 ± 0.51c | 1.15 | 3.92 ± 0.58b,d | 0.85 |
| rOmp31 | 3.85 ± 0.50c | 1.25 | 2.96 ± 0.36c | 1.81 |
| H38 | 2.97 ± 0.45c | 2.13 | 2.35 ± 0.49c | 2.42 |
a
The content of bacteria in spleens is represented as the mean log CFU ± SD per group.
b
Significantly different from PBS-immunized mice (P < 0.05) as estimated by Dunnett's test.
c
Significantly different from PBS-immunized mice (P < 0.01) as estimated by Dunnett's test.
d
Significantly different from rOmp31-immunized mice (P < 0.05) as estimated by Dunnett's test.