FIG. 1.

GXM clearance from serum and accumulation in the liver and spleen in WT, CD14^−/−, TLR2^−/−, and CD18 mutant mice. Mice were injected i.v. with 75 μg strain 6 or J11a GXM. GXM concentrations then were measured in the serum, liver, and spleen on days 1, 2, 4, 8, and 16 after injection. The data are expressed as the mean ± SEM of four WT and two mutant mice per day. *, P ≤ 0.01.