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. 2026 Feb 27;15(3):69. doi: 10.21037/tp-2025-1-871

Table 2. Comparison of clinical and pathological characteristics of thyroid cancer patients in CAYAs and older adults.

Characteristics ≤25 years, n (%) >25 years, n (%) Log rank χ2 P value
Sex 2.706 0.10
   Female 162 (29.7) 235 (43.1)
   Male 72 (13.2) 76 (13.9)
Bilateralism 12.960 <0.01
   Yes 45 (8.3) 27 (5.0)
   No 189 (34.7) 284 (52.1)
Multifocality 37.898 <0.01
   Yes 81 (14.9) 39 (7.2)
   No 153 (28.1) 272 (49.9)
PTMC 15.849 <0.01
   Yes 98 (18.0) 80 (14.7)
   No 136 (25.0) 231 (42.4)
Subtype 1.235 0.26
   Invasive subtype 15 (2.8) 28 (5.1)
   Non-invasive subtype 219 (40.2) 283 (51.9)
Extrathyroidal extension 31.583 <0.01
   Yes 196 (36.0) 192 (35.2)
   No 38 (7.0) 119 (21.8)
Nodular goiter 1.895 0.16
   Yes 10 (1.8) 21 (3.9)
   No 224 (41.1) 289 (53.0)
Lymphatic metastasis 13.554 <0.01
   Yes 160 (29.4) 164 (30.1)
   No 74 (13.6) 221 (40.6)
Postoperative recurrence 4.502 0.03
   Yes 31 (5.7) 24 (4.4)
   No 203 (37.2) 287 (52.7)

CAYAs, children, adolescents, and young adults; PTMC, papillary thyroid microcarcinoma.