RB	Retinoblastoma
CDK	Cyclin dependent kinase
CDK4/6i	Cyclin dependent kinase 4/6 inhibitors
PARPi	Poly (ADP-ribose) polymerase inhibitors
CIN	Chromosomal instability
BETi	Bromodomain and extraterminal domain inhibitors
DOX	Doxorubicin
STS	Soft tissue sarcoma
PFS	Progression free survival
TNBC	Triple negative breast cancer
DREAM	Dimerization partner, RB-like, E2F, and the multi-vulval class B
HDACs	Histone deacetylases
CHR	Cell-cycle gene homology regions
ESC	Embryonic stem cell
CSC	Cancer stem cells
EMT	Epithelial-mesenchymal transition
DSB	Double-strand breaks
NHEJ	Non-homologous end joining
HR	Homologous recombination
ER	Estrogen receptor
5-FU	5-Fluorouracil
CRISPR	Clustered regularly interspaced short palindromic repeats