Table 2.

Blood pressure by treatment group regardless of pharmacologic therapy

	Placebo		Metformin		Intensive lifestyle
Blood pressure (mmHg)	Systolic	Diastolic	Systolic	Diastolic	Systolic	Diastolic
Baseline (means ± SD)	123.5 ± 14.4	78.0 ± 9.2	124.0 ± 14.9	78.2 ± 9.5	123.7 ± 14.8	78.6 ± 9.2
Change at year 1	− 0.90 ± 0.4	−0.89 ± 0.2	−0.91 ± 0.4*	−1.26 ± 0.2*	−3.4 ± 0.4*	−3.6 ± 0.2*
Change at year 2	−0.52 ± 0.4	−1.07 ± 0.2	−0.94 ± 0.4*	−1.06 ± 0.2*	−3.4 ± 0.4*	−3.33 ± 0.2*
Change at year 3	−0.57 ± 0.5	−1.88 ± 0.3	−0.29 ± 0.5*	−1.59 ± 0.3*	−3.27 ± 0.5*	−3.82 ± 0.3*

Data are means ± SE unless otherwise noted.

^*P < 0.001 vs. placebo for changes in mean over time.