. Author manuscript; available in PMC: 2005 Dec 6.

Published in final edited form as: N Engl J Med. 2004 Jun 10;350(24):2441–2451. doi: 10.1056/NEJMoa032196

Table 1.

Patients with PONV.

	Received Intervention
Intervention	*Yes PONV^/N^†(%)**	No PONV/N (%)	Relative risk (% [95% CI])	P (chi-square)
Ondansetron	735/2576 (28.5)	996/2585 (38.5)	−26.0 (−19.9 to −31.5)	<0.001
Dexamethasone	739/2596 (28.5)	992/2565 (38.7)	−26.4 (−20.4 to −31.9)	<0.001
Droperidol	742/2573 (28.8)	989/2588 (38.2)	−24.5 (−18.4 to −30.2)	<0.001
Propofol vs. inhalational anesthetics	1066/3427 (31.1)	665/1734 (38.4)	−18.9 (−12.3 to −25.0)	<0.001
Air with 30% oxygen vs. nitrous oxide	668/2146 (31.1)	755/2131 (35.4)	−12.1 ( −4.3 to −19.3)	0.003
Remifentanil vs. fentanyl	827/2386 (34.7)	792/2403 (33.0)	5.2 (13.8 to −2.9)	0.21

PONV = Number of patients suffering postoperative nausea, vomiting, or both.

^†

N = total number of patients randomized with complete outcome for the intervention under investigation. The data are based on all 5161 randomized patients that completed the study with the exceptions of carrier gas (N = 4277) and remifentanil (N = 4789) to assure group comparability (see also figure 1).