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. 2005 Dec 8;116(1):49–58. doi: 10.1172/JCI24787

Figure 4.

Figure 4

KLF2 mediates a global antiinflammatory program in endothelial cells. (A) Protein levels of cytokines in supernatants of HUVECs infected with the indicated virus and then incubated with either normal media or IL-1β (10 U/ml) for 24 hours. Samples were analyzed by multiplex ELISA or cytokine chip. IP-10, IFN-γ–inducible protein 10. (B) Regulation of PTGDS gene expression by KLF2 and/or IL-1β. (C) ELISA of 15d-PGJ2 after extraction from supernatants of cells infected with the indicated virus for 24 hours. (D) ELAFIN secretion measured by ELISA from supernatants under conditions described in A. All data are expressed as mean ± SEM (n = 3). *P < 0.05, **P < 0.01 vs. control; Student’s t test.