TABLE 2.
Profiles of the 11 patients with HEV viremia
| Patient no. | Age (yr)/sexa | Locationb | Yr of onset | Peak T. Bil (mg/dl)c | Peak ALT (IU/liter)d | Peak AST (IU/liter)e | OD at 450 nmf
|
Name of HEV isolate | HEV genotype | |
|---|---|---|---|---|---|---|---|---|---|---|
| IgM-class anti-HEV | IgG-class anti-HEV | |||||||||
| 1 | 55/M | Hokkaido | 1997 | 4.2 | 4,850 | 3,680 | 2.105 | >3.000 | HE-JA1 | IV |
| 2 | 71/M | Hokkaido | 1998 | 6.2 | 4,623 | 5,931 | 2.665 | >3.000 | HE-JA2 | IV |
| 3 | 42/M | Hokkaido | 1998 | 24.0 | 1,744 | 1,255 | >3.000 | >3.000 | HE-JA3 | IV |
| 4 | 44/M | Hokkaido | 2000 | 9.7 | 1,562 | 1,385 | >3.000 | 2.660 | HE-JA4 | III |
| 5 | 46/M | Iwate | 1998 | 4.1 | 2,824 | 1,624 | 2.255 | >3.000 | HE-JA5 | III |
| 6 | 47/F | Iwate | 1999 | 0.8 | 1,430 | 1,415 | >3.000 | >3.000 | HE-JA6 | III |
| 7 | 72/M | Iwate | 2001 | 20.0 | 914 | 1,050 | >3.000 | >3.000 | HE-JA7 | III |
| 8 | 56/M | Iwate | 2001 | 5.7 | 2,066 | 539 | >3.000 | >3.000 | HE-JA8 | III |
| 9 | 45/M | Fukushima | 2001 | 1.5 | 2,290 | 1,191 | >3.000 | >3.000 | HE-JA9 | III |
| 10 | 40/F | Tokyo | 1993 | 2.4 | 1,019 | 590 | >3.000 | >3.000 | HE-JA10 | III |
| 11 | 50/M | Yamanashi | 2001 | 19.2 | 1,886 | 877 | 1.638 | >3.000 | HE-JA11 | III |
a
M, male; F, female.
b
Arranged from north to south in Japan.
c
T. Bil., total bilirubin (normal range, 0.2 to 1.0 mg/dl).
d
Normal range, 4 to 30 IU/liter.
e
Normal range, 11 to 30 IU/liter.
f
Detected at admission.