Table 4.

Blood biochemistry parameters (mean ± SD) following 5-week repeated intravenous administration of AHT-102 in hCD3EDG mice on day 43 of the recovery period

Parameters	Unit	Sex	Test date	Vehicle	AHT-102 (1.5 mg/kg)	AHT-102 (4.5 mg/kg)	AHT-102 (13.65 mg/kg)
ALB	g/L	Female	R43	37.2 ± 0.66	36.9 ± 1.60	36.7 ± 0.54	36.9 ± 0.63
TP	g/L	Female	R43	44.0 ± 1.31	44.2 ± 1.72	43.8 ± 1.22	44.5 ± 0.86
ALB	g/L	Male	R43	34.9 ± 1.07	35.3 ± 0.94	35.2 ± 0.86	35.4 ± 0.78
A/G		Male	R43	3.78 ± 0.224	3.75 ± 0.375	4.19 ± 0.373	3.95 ± 0.474

R recovery phase, n = 5

A/G albumin/globulin ALB normal albumin, TP total protein