Figure 5.

Topological comparisons for three related linkers (methylene, ether, thioether) and three related sidechains (benzene, p-fluorobenzene, p-methylbenzene) and associated Venn diagrams showing the intersections of fragments in the accompanying iso-tables for the top 100 (or max), top 50, and top 20 ranked entries from the HMS/HMS iso-library.