Table 1.

Diagnostic parameters of serum MR, CD163, CEA, CA19-9 and CA72-4 in detection of colorectal cancer patients

	AUC	Sen (%)	Spe (%)	Acc (%)	PPV (%)	NPV (%)	Pos LR	Neg LR
MR	0.7205	54.82	80.46	66.01	89.22	50.33	2.81	0.56
CD163	0.7463	62.65	80.46	71.15	90.43	55.07	3.21	0.46
MR $+$ CD163	0.7968	69.28	77.01	71.94	81.19	55.07	3.01	0.40
CEA	0.7159	60.24	79.31	66.80	84.75	51.11	2.91	0.50
CA19-9	0.6276	36.75	88.51	54.55	85.92	44.00	3.20	0.71
CA72-4	0.6387	31.93	95.40	53.75	92.98	42.35	6.94	0.82
CEA $+$ CA19-9	0.7385	50.60	90.80	63.64	91.30	49.07	5.50	54.40
CEA $+$ CA72-4	0.7559	68.67	78.16	71.94	85.71	56.67	3.14	0.40
CA19-9 $+$ CA72-4	0.6937	50.00	83.91	61.66	85.57	46.79	3.11	0.60
MR $+$ CEA	0.7831	69.88	79.31	73.12	86.56	57.98	3.38	0.38
MR $+$ CA19-9	0.7413	63.86	80.46	69.57	86.19	53.85	3.27	0.45
MR $+$ CA72-4	0.7482	73.49	67.82	71.54	81.33	57.28	2.28	0.39
CD163 $+$ CEA	0.8141	71.08	81.61	74.70	88.06	59.66	3.87	0.35
CD163 $+$ CA19-9	0.7783	60.24	87.36	69.57	90.09	53.52	4.77	0.46
CD163 $+$ CA72-4	0.7781	64.46	79.31	69.57	85.60	53.90	3.16	0.45

Note: AUC, area under curve. Sen, sensitivity. Spe, specificity. Acc, accuracy. PPV, positive predictive value. NPV, negative predictive value. Pos LR, positive likelihood ratio. Neg LR, negative likelihood ratio.