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. 2026 Apr 1;13:1753313. doi: 10.3389/fmed.2026.1753313

Table 4.

Association between CD3 + CD4+ T-cell count and ARDS: dose–response relationship and threshold effect analysis.

Variables Adjusted OR (95% CI) p-value
T cells CD3 + CD4 + count (continuous variable)
Per 1-cell/μL increase 1.00 (1.00 ~ 1.00) 0.009
Per 50-cell/μL increase 0.89 (0.82 ~ 0.97) 0.009
Per 100-cell/μL increase 0.80 (0.67 ~ 0.94) 0.009
Threshold effect analysis
≥227 cells/μL (per 50-cell/μL increase) 1.244 (0.646 ~ 2.396) 0.5130
<227 cells/μL (per 50-cell/μL increase) 0.832 (0.735 ~ 0.941) 0.0035

Analysis adjusted for age, sex, albumin, Tbil, neutrophil count, C-reactive protein (CRP), procalcitonin (PCT), cerebrovascular disease, and heart failure. OR, odds ratio; CI, confidence interval.