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. 2026 Apr 1;20:1702124. doi: 10.3389/fnins.2026.1702124

Figure 7.

Panel A shows a boxplot of V1 Pre Pain Condition NSR values across four task assays: resting, pointing, peg, and drawing. Panel B displays a similar boxplot for V1 Pain Condition. Panel C contains three ANOVA tables summarizing statistical tests: Kruskal-Wallis for pre pain control and pain conditions, and Friedman’s test for control versus pain. Panels D, E, and F are heatmaps showing pairwise NSR ranksum test results for V1, V2, and V3 across resting, peg, pointing, and drawing tasks for control and pain conditions, with a color scale ranging from blue to yellow.

Statistical tests of the Gamma parameters for facial micro-movements. (A) Control condition (pre-pain) shows statistically significant differences in the Gamma NSR parameter according to the non-parametric Kruskal–Wallis test for the ophthalmic area V1 across all tasks. The MATLAB Multcompare test reveals p < 0.01 for all pairwise comparisons relative to the resting task. (B) During the pain condition, these differences are accentuated. (C) Stats table for comparisons A and B and for the control vs. pain comparison according to the Friedman’s test. All comparisons yield p < 10−10. (D) Pairwise comparisons of NSR rank-sum test in ophthalmic area V1, (E) maxillary area V2 and (F) mandibular area V3.