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. 2026 Apr 1;20:1702124. doi: 10.3389/fnins.2026.1702124

Figure 9.

Panel A shows a color-coded matrix representing Earth Mover’s Distance (EMD) comparisons for control versus pain conditions across multiple tasks and states, with a color bar indicating similarity from zero to one. Panel B displays a hierarchical clustering dendrogram labeled “Gamma NSR 4 Tasks x 2 States” with distance between subtypes on the y-axis and clusters of tasks pre- and post-intervention on the x-axis using colored branches.

Individualized probability distribution families across participants are compared pairwise using the EMD and grouped into self-emerging clusters. (A) Matrix of EMD values denoting the normalized distance (color bar) for each participant in the V1 area (the most significantly impacted by tasks and pain) – PRE refers to the control (before pain condition) and POST refers to the pain condition. (B) Tree clustering of the participants into 8 groups according to the EMD values in (A), obtained from the distributions of gamma NSR parameters empirically estimated. Cluster composition of control vs. pain PDF percentages is detailed in the main text.