TABLE 2.

GEE results; estimated regression coefficients and statistical values of significance for comparison to standard

Antimicrobial agent	Estimated regression coefficients and significancea
	Site-related differencesb				Method-related differencesc
	Site 2		Site 3		PML MH HTM		MH LHB NAD		IST LHB NAD		IST HTM
	Estimate	P value	Estimate	P value	Estimate	P value	Estimate	P value	Estimate	P value	Estimate	P value
Amox-clav acidd	−0.4600	<0.0001	−0.2850	0.0934	0.4550	<0.0001	0.2600	<0.0001	0.1319	0.0046	0.2733	<0.0001
Azithromycin	−0.5550	<0.0001	−0.3175	0.0067	0.2575	0.0004	0.1550	<0.0001	0.0900	0.1346	0.1500	0.0188
Cefaclor	−1.4250	<0.0001	−0.6875	0.0005	1.2875	<0.0001	0.4750	<0.0001	−0.0300	0.6856	−0.1600	0.0690
Cefixime	−0.7786	<0.0001	−0.4607	0.0078	0.8893	<0.0001	0.2214	<0.0001	−0.1000	0.1556	−0.1571	0.0287
Cefprozil	−1.2250	<0.0001	−0.9575	<0.0001	1.0275	<0.0001	0.5350	<0.0001	−0.2400	0.0020	−0.0700	0.3047
Ceftriaxone	−0.5000	<0.0001	−0.2700	0.0901	0.5300	<0.0001	0.0100	0.7455	−0.0200	0.7387	−0.1100	0.0134
Cefuroxime	−0.7900	<0.0001	−0.8550	<0.0001	0.7520	<0.0001	0.2200	0.0001	−0.0900	0.0673	−0.0800	0.1122
Chloramphenicol	−0.8100	<0.0001	−0.2650	0.0974	0.5850	<0.0001	0.1400	0.0001	−0.0100	0.8083	0.0100	0.7629
Ciprofloxacin	−0.0200	0.0979	0.0000	1.0000	0.0500	0.0310	0.0000	1.0000	0.0800	0.0089	0.2300	<0.0001
Clarithromycin	−0.2300	<0.0001	0.1450	0.2044	0.0850	0.0821	−0.0400	0.2734	−0.0200	0.6947	0.0400	0.4917
Doxycycline	−0.4700	<0.0001	0.0100	0.9278	0.4600	<0.0001	−0.1000	0.0003	0.3800	<0.0001	0.9100	<0.0001
Erythromycin	−0.4900	<0.0001	−0.0300	0.7874	0.3200	<0.0001	0.1500	<0.0001	0.0800	0.1660	−0.0100	0.8694
Gemifloxacin	0.0000	1.0000	0.0000	1.0000	−0.0200	0.1531	−0.0300	0.0786	0.0100	0.3149	0.0400	0.0979
Grepafloxacin	−0.0750	0.0002	0.0925	0.1551	0.0775	0.0049	−0.0750	0.0002	0.0500	0.2218	0.4800	<0.0001
Levofloxacin	−0.0550	0.0056	−0.0175	0.6902	0.0475	0.0352	−0.0150	0.1758	0.2300	<0.0001	0.4500	<0.0001
Ofloxacin	−0.0750	0.0010	−0.0225	0.7053	0.1125	0.0004	−0.0050	0.7053	0.3500	<0.0001	0.5300	<0.0001
Trovafloxacin	−0.0450	0.0786	−0.0275	0.7171	−0.0125	0.6951	−0.1150	<0.0001	0.1200	0.0199	0.4200	<0.0001

^aBoldface, significant at >0.25-dilution difference. Regression coefficients are shown as doubling dilution differences above (positive values) or below (negative values) standard, and statistical values of significance (P values are compared to standard).

^bCompared to site 1.

^cCompared to MH HTM.

^dAmox-clav acid, amoxicillin-clavulanic acid.