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. 2026 Apr 10;18:597831. doi: 10.2147/IJWH.S597831

Table 1.

The Prevalence and YLDs of Pelvic Inflammatory Disease and Their EAPCs from 1990 to 2021 at the Global and Regional Levels

Characteristics Prevalence YLDs
Number of Cases, Thousand, 1990 (95% UI) ASR per 100,000 Population, 1990 (95% UI) Number of Cases, Thousand, 2021 (95% UI) ASR per 100,000 Population, 2021 (95% UI) EAPC, 1990–2021 (95% UI) Number of Cases, Thousand, 1990 (95% UI) ASR per 100,000 Population, 1990 (95% UI) Number of Cases, Thousand, 2021 (95% UI) ASR per 100,000 Population, 2021 (95% UI) EAPC, 1990–2021 (95% UI)
Global 626.00(473.63–805.67) 25.82(19.66–32.82) 85.18(52.44–129.61) 27.02(20.24–34.89) −0.04 (−0.09–0.00) 1009.96(743.84–1330.47) 3.51(2.20–5.33) 177.20(108.36–260.12) 3.68(2.27–5.63) −0.04 (−0.09–0.01)
Cause
Chlamydial infection 143.26(106.14–194.78) 5.80(4.43–7.70) 232.25(169.27–318.93) 6.22(4.61–8.40) 0.04 (−0.02–0.09) 19.55(11.52–30.46) 0.79(0.49–1.21) 31.72(18.51–49.90) 0.85(0.51–1.31) 0.04 (−0.02–0.10)
Gonococcal infection 39.21(28.41–51.80) 1.53(1.12–2.01) 50.27(36.00–69.16) 1.31(0.94–1.78) −0.8 (−0.91–−0.69) 5.39(3.12–8.58) 0.21(0.12–0.33) 6.92(3.90–11.29) 0.18(0.10–0.29) −0.79 (−0.90–−0.68)
Other sexually transmitted infections 443.54(329.45–577.01) 18.49(13.92–23.85) 727.44(535.82–966.40) 19.49(14.54–25.56) −0.01 (−0.05–0.03) 60.24(36.71–92.53) 2.51(1.57–3.84) 98.93(58.71–152.88) 2.65(1.63–4.09) −0.01 (−0.05–0.03)
Socio-demographic index
High SDI 104.74(75.80–139.51) 23.70(17.53–30.99) 121.96(91.92–157.31) 25.12(19.43–31.49) −0.08 (−0.18–0.02) 14.36(8.41–21.94) 3.25(1.91–4.96) 16.70(10.25–25.15) 3.44(2.17–5.14) −0.08 (−0.18–0.02)
High-middle SDI 99.93(72.20–134.93) 19.95(14.81–26.22) 130.23(94.57–172.97) 21.01(15.80–27.25) 0.25 (0.20–0.31) 13.66(8.15–21.21) 2.73(1.64–4.18) 17.79(10.68–28.09) 2.87(1.74–4.43) 0.25 (0.20–0.31)
Middle SDI 155.63(114.15–203.38) 20.35(15.26–26.33) 279.88(206.08–370.45) 23.29(17.49–29.84) 0.37 (0.34–0.40) 21.22(12.81–32.36) 2.77(1.71–4.21) 38.15(22.48–58.87) 3.17(1.93–4.84) 0.37 (0.34–0.40)
Low-middle SDI 162.04(125.51–207.96) 33.52(26.41–42.10) 289.72(211.80–388.59) 30.72(22.90–40.60) −0.55 (−0.65–−0.45) 21.92(13.81–33.40) 4.53(2.89–6.84) 39.41(23.46–60.82) 4.18(2.52–6.42) −0.53 (−0.63–−0.44)
Low SDI 103.16(81.54–129.07) 50.35(40.43–62.22) 187.57(135.62–252.57) 38.23(28.28–50.35) −1.39 (−1.58–−1.19) 13.94(9.05–21.16) 6.80(4.42–10.22) 25.44(15.22–39.15) 5.19(3.13–7.90) −1.37 (−1.56–−1.17)
GBD regions
Andean Latin America 6.57(4.84–8.78) 38.88(29.16–50.75) 13.49(10.36–17.32) 40.47(31.73–51.36) 0.11 (0.07–0.16) 0.90(0.53–1.37) 5.30(3.26–8.04) 1.84(1.10–2.82) 5.53(3.35–8.44) 0.12 (0.07–0.17)
Australasia 4.83(3.52–6.45) 46.01(34.71–60.41) 6.88(5.02–9.16) 47.74(36.38–63.01) 0.11 (0.08–0.13) 0.66(0.38–1.06) 6.31(3.77–9.97) 0.94(0.55–1.47) 6.54(3.87–10.20) 0.11 (0.08–0.13)
Caribbean 4.05(3.05–5.31) 24.66(18.80–31.97) 5.26(3.80–6.99) 23.24(17.29–30.17) −0.15 (−0.32–0.03) 0.55(0.34–0.86) 3.36(2.08–5.22) 0.72(0.42–1.12) 3.17(1.89–4.87) −0.14 (−0.32–0.03)
Central Asia 9.30(6.77–12.51) 30.81(23.04–40.68) 15.36(10.98–20.71) 32.25(23.68–42.23) 0.1 (0.04–0.16) 1.27(0.74–2.00) 4.20(2.52–6.44) 2.09(1.25–3.34) 4.40(2.65–6.91) 0.1 (0.04–0.17)
Central Europe 12.90(9.29–17.16) 22.67(17.20–29.62) 11.62(8.79–15.03) 23.57(18.57–29.59) 0.24 (0.16–0.31) 1.77(1.03–2.73) 3.10(1.81–4.80) 1.59(0.97–2.41) 3.22(1.97–4.84) 0.23 (0.16–0.31)
Central Latin America 16.10(11.84–21.02) 23.10(17.34–29.86) 30.44(22.79–39.85) 24.32(18.51–31.15) 0.08 (−0.01–0.16) 2.20(1.29–3.33) 3.16(1.89–4.76) 4.17(2.43–6.40) 3.33(2.01–5.05) 0.08 (−0.01–0.17)
Central Sub-Saharan Africa 9.72(7.57–12.36) 43.94(34.71–55.22) 22.26(15.92–29.73) 38.02(27.68–49.67) −0.82 (−0.92–−0.71) 1.31(0.80–1.96) 5.94(3.69–8.86) 3.03(1.74–4.74) 5.17(3.08–7.95) −0.79 (−0.89–−0.68)
East Asia 101.50(71.83–137.82) 18.30(13.40–24.14) 132.88(96.85–177.02) 19.43(14.71–25.28) 0.28 (0.13–0.44) 13.88(8.44–21.45) 2.50(1.52–3.90) 18.15(10.81–28.46) 2.65(1.62–4.09) 0.28 (0.13–0.44)
Eastern Europe 29.00(21.34–38.96) 26.85(20.37–34.81) 23.92(16.76–32.78) 24.13(17.88–31.62) −0.4 (−0.58–−0.23) 3.95(2.37–6.10) 3.66(2.20–5.54) 3.27(1.91–5.20) 3.30(1.95–5.05) −0.4 (−0.57–−0.23)
Eastern Sub-Saharan Africa 31.98(24.93–40.73) 42.25(33.62–52.63) 60.81(43.83–81.05) 32.09(23.63–42.17) −1.38 (−1.59–−1.18) 4.33(2.78–6.57) 5.72(3.70–8.57) 8.28(4.91–13.00) 4.37(2.58–6.68) −1.37 (−1.57–−1.16)
High-income Asia Pacific 34.28(25.27–45.22) 39.70(29.62–50.95) 32.36(24.27–42.39) 43.51(33.07–55.26) 0.39 (0.34–0.44) 4.70(2.78–7.14) 5.44(3.21–8.21) 4.42(2.65–6.76) 5.95(3.62–9.05) 0.38 (0.33–0.43)
High-income North America 39.29(27.96–52.40) 26.31(19.42–34.69) 43.44(33.61–54.78) 26.23(20.62–32.52) −0.65 (−0.86–−0.43) 5.39(3.10–8.45) 3.61(2.08–5.57) 5.96(3.74–8.87) 3.60(2.29–5.37) −0.64 (−0.85–−0.43)
North Africa and Middle East 22.49(16.19–29.87) 17.05(12.68–22.24) 52.22(36.63–70.37) 17.18(12.68–22.59) 0.24 (0.10–0.38) 3.07(1.83–4.77) 2.33(1.41–3.54) 7.14(4.17–11.27) 2.35(1.39–3.66) 0.25 (0.10–0.39)
Oceania 1.28(1.01–1.58) 48.91(38.66–60.85) 1.65(1.17–2.26) 26.07(18.84–35.35) −1.29 (−1.62–−0.96) 0.17(0.10–0.26) 6.61(4.00–9.81) 0.23(0.13–0.36) 3.57(2.09–5.66) −1.26 (−1.59–−0.93)
South Asia 166.28(128.52–214.24) 36.60(28.80–46.33) 305.09(220.84–411.95) 33.13(24.62–44.24) −0.59 (−0.74–−0.44) 22.48(13.97–34.55) 4.95(3.15–7.48) 41.46(24.68–64.58) 4.50(2.68–6.97) −0.58 (−0.73–−0.42)
Southeast Asia 21.56(15.42–28.65) 10.23(7.54–13.32) 34.79(25.76–45.73) 9.95(7.44–12.87) −0.14 (−0.19–−0.09) 2.95(1.73–4.56) 1.40(0.83–2.15) 4.75(2.86–7.39) 1.36(0.83–2.10) −0.14 (−0.19–−0.09)
Southern Latin America 7.54(5.63–9.84) 32.33(24.42–41.78) 10.75(7.69–14.35) 31.48(22.82–41.42) −0.18 (−0.23–−0.14) 1.03(0.59–1.61) 4.42(2.59–6.77) 1.48(0.85–2.30) 4.32(2.59–6.65) −0.18 (−0.23–−0.13)
Southern Sub-Saharan Africa 11.63(8.73–15.35) 47.17(36.52–61.24) 15.71(11.14–21.25) 36.35(26.28–48.62) −1.69 (−2.13–−1.24) 1.58(0.98–2.47) 6.40(3.99–10.02) 2.14(1.25–3.40) 4.95(2.89–7.76) −1.67 (−2.11–−1.23)
Tropical Latin America 7.26(5.54–9.29) 10.66(8.28–13.44) 38.91(29.68–50.75) 32.89(25.40–42.26) 4.12 (2.87–5.40) 0.99(0.62–1.52) 1.46(0.92–2.21) 5.30(3.29–8.18) 4.48(2.84–6.88) 4.11 (2.86–5.38)
Western Europe 19.21(13.49–25.72) 10.29(7.41–13.55) 28.61(21.04–36.97) 15.31(11.56–19.41) 1.08 (0.78–1.38) 2.63(1.54–4.18) 1.41(0.83–2.23) 3.92(2.38–6.07) 2.10(1.33–3.20) 1.07 (0.77–1.37)
Western Sub-Saharan Africa 69.24(53.04–87.94) 82.67(64.54–104.29) 123.52(86.51–173.70) 55.25(39.73–76.69) −1.98 (−2.27–−1.69) 9.35(6.04–13.82) 11.16(7.14–16.74) 16.71(10.05–25.82) 7.48(4.62–11.65) −1.97 (−2.25–−1.68)

Abbreviations: ASR, Age-standardized rate; YLD, years lived with disability; EAPC, estimated annual percentage change; UI, uncertainty interval.