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Mass spectrometry analysis of clinical samples from patients with hepatitis C. (A and B) These two samples were taken 6 months apart from a patient infected with an HCV strain of genotype 1b. A complete change of the HCV population was observed during that period. (C and D) These two samples were taken 6 months apart from a patient infected with an HCV strain of genotype 1a. No changes in the HCV population could be observed.
