TABLE 4.
Resistance patterns in relation to clusters of M. tuberculosis strains belonging to the Beijing genotype
| Cluster size | Pattern fora:
|
No. of strains | Mutation in rpoB gene (no. of strains) | |||
|---|---|---|---|---|---|---|
| E | H | Rif | Str | |||
| 15 | R | R | R | R | 10 | 531 TCG→TTG (9) |
| 531 TCG→TGG (1) | ||||||
| S | R | S | R | 2 | ||
| S | S | S | S | 2 | ||
| R | R | S | R | 1 | ||
| 12 | S | S | S | R | 6 | |
| R | R | R | R | 4 | 513 CAA→CTA (3) | |
| 531 TCG→TTG (1) | ||||||
| R | S | S | S | 1 | ||
| S | R | S | S | 1 | ||
| 9 | S | R | R | R | 3 | 531 TCG→TTG (2) |
| 516 GAC→GTC (1) | ||||||
| S | R | S | R | 3 | ||
| R | R | R | R | 2 | 531 TCG→TTG (2) | |
| S | S | S | S | 1 | ||
| 5 | R | R | R | R | 5 | 531 TCG→TTG (5) |
| 2 | S | S | S | R | 1 | |
| S | S | S | S | 1 | ||
| 2 | S | R | S | R | 2 | |
| 2 | S | S | S | S | 2 | |
| 2 | S | S | S | S | 2 | |
a
E, ethambutol; H, isoniazid; Rif, rifampin; Str, streptomycin. R, resistant; S, susceptible.