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. 2002 Dec;3(12):1209–1214. doi: 10.1093/embo-reports/kvf241

Figure 2.

Figure 2

The N-terminal domain of Aurora-A confers degradation capacity on the C-terminal domain of Aurora-B. (A) Schematic domain structure of Aurora-A, Aurora-B and Aurora-A/B chimera. (B) An interphase extract (20 μl) was complemented (INT+Fzr) or not (INT-Fzr) with Fizzy-Related mRNA. One hour later both extracts were supplemented with 2 μl of either in vitro translated 35S-labelled A/B chimera or the Dbox mutated form of this chimerical protein. Samples of 2 μl were then taken at different times and the two chimeras were analysed by autoradiography.