Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Main genotypes conferring drug resistance in 221 subjects failing antiretroviral therapy
| Drug family | Mutation | No. (%) of subjects |
|---|---|---|
| NA | T215Y/F | 112 (50.7) |
| M184V/I | 109 (49.3) | |
| M41L | 91 (41.2) | |
| E44D/A ± V118I | 45 (20.4) | |
| ≥4 NAMs | 42 (20) | |
| NNRTI | K103N | 60 (27.2) |
| Y181C | 37 (16.7) | |
| G190A | 30 (13.6) | |
| PI | L90M | 68 (31) |
| V82A/F/T | 52 (23.5) | |
| M46L/I | 41 (18.5) | |
| MNRa | Insert 67/69b | 2 (0.9) |
| Q151M complex | 1 (0.45) |
MNR, multinucleoside resistance.
Insert 67/69, codon 67 and 69 insertions.
