Table 3.

Thyroid hormone levels in serum and brains of dams and their offspring following PCN treatment. Thyroid hormones T3, T4, their free fraction fT4 and fT3, and TSH were quantified in dams at GD21 and PND21 and in their offspring at GD21, PND4, and PND21. The results shown are percentage change compared to the control. For dams n = 8. For serum measurements in offspring, n = 20 at GD21, n = 8 at PND4, n = 8 at PND21, for brain measurements in offspring, n = 50 at GD21, n = 30 at PND4, n = 24 at PND21. Significant increase in thyroid hormone levels between treated and controls is indicated in orange, while decrease is shown in green. Dunnett LSD test: *p-value < 0.01