Table 1.

Baseline Demographics, Clinical Characteristics, and Treatment Summary.

	Standard regimen (41.4 Gy) (n = 34)	Intensified Regimen (50.4 Gy) (n = 36)	P-value
Age [years; mean (SD)]	59.85 (9.66)	59.41 (10.98)	0.861a
Sex [n (%)]			0.497b
•Male	20 (58.8%)	24 (66.7%)
•Female	14 (41.2%)	12 (33.3%)
Location of Lesion [n (%)]			0.808b
•Middle Thoracic Esophagus	14 (41.1%)	17 (47.2%)
•Lower Thoracic Esophagus	16 (47.1%)	17 (47.2%)
•Gastroesophageal Junction	4 (11.8%)	2 (5.6%)
Histology [n (%)]			0.549b
•SCC	26 (76.5%)	31 (86.1%)
•ADC	7 (20.6%)	4 (11.1%)
•Undifferentiated	1 (2.9%)	1 (2.8%)
Lesion Grade [n (%)]			0.087b
•Well differentiated	12 (42.9%)	4 (15.4%)
•Moderately differentiated	11 (39.3%)	15 (57.7%)
•Poorly differentiated	5 (17.9%)	7 (26.9%)
T stage [n (%)]			0.708b
•T1	1 (2.9%)	0 (0%)
•T2	4 (11.8%)	5 (13.9%)
•T3	24 (70.6%)	24 (66.7%)
•T4	5 (14.7%)	7 (19.4%)
N stage [n (%)]			0.791b
•N0	3 (8.8%)	2 (5.6%)
•N1	15 (44.1%)	13 (36.1%)
•N2	14 (41.2%)	19 (52.8%)
•N3	2 (5.9%)	2 (5.6%)
Lesion length [cm; mean (SD)]	4.45 (1.84)	4.77 (1.76)	0.530a
Radiotherapy
•Completion of RT [n (%)]	34 (100%)	36 (100%)	−
•Duration [days; mean (SD)]	32.32 (5.40)	39.36 (3.73)	<0.001a
•RT Violation [n (%)]	6 (17.6%)	7 (19.4%)	0.14b
Chemotherapy
•Completion of CT [n (%)]	28 (82.3%)	27 (75%)	0.254b
•Number of cycles [n; mean (SD)]	3.88 (1.03)	4.83 (0.84)	<0.001a
Surgery
Number underwent Sx [n (%)]	23 (67.6%)	21 (58.3%)	0.420b
Type of Sx			0.193b
•Esophagectomy	12 (52.2%)	13 (61.9%)
•Esophagogastrectomy	11 (47.8%)	8 (38.1%)
Duration from completion of RT to Sx [weeks; mean (SD)]	9.94 (1.43)	12.69 (1.23)	0.652a

P-value of < 0.05 was considered statistically significant.

SD: standard deviation; SCC: Squamous Cell Carcinoma; ADC: Adenocarcinoma.

^aStudent T-test.

^bChi-squared test.