Table 2.

Clinical characteristics of the 74 Chinese CRC patients with pathogenic germline mutations

Characteristic	Group P-MMR	Group P-Non-MMR	P value
Total	33 (44.59%)	41 (55.41%)
Age			0.1047
< 50 years	15 (45.45%)	12 (29.27%)
≥ 50 years	15 (45.45%)	27 (65.85%)
Unknown	3 (9.09%)	2 (4.88%)
Gender			0.0648
Female	20 (60.61%)	16 (39.02%)
Male	13 (39.39%)	25 (60.98%)
TMB level			0.0003
TMB-high	20 (60.61%)	8 (19.51%)
TMB-low	13 (39.39%)	33 (80.49%)
MSI status			< 0.0001
MSI-H	18 (54.55%)	3 (7.32%)
MSS	15 (45.45%)	38 (92.68%)

Note: Boldface indicate statistical significance