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E-cadherin reactivity in metastatic "lobular" carcinoma (case 2). A: Well-differentiated invasive ductal carcinoma (Hematoxylin and eosin, left) exhibiting weak cell membrane positivity for E-cadherin (Immunoperoxidase stain for E-cadherin, right). B: Nodal metastasis demonstrating strong cell membrane immunoreactivity for E-cadherin; higher magnification of tumor cells (inset) (Immunoperoxidase stain for E-cadherin).
