Table 2. Affymetrix analysis of genes regulated by antisense MIF transfection.
Affymetrix ID no. | GenBank accession no. | Description | Fold change | P value† |
---|---|---|---|---|
205943_at‡ | NM_005651 | Tryptophan 2,3-dioxygenase (TDO2) | −3.15 ± 0.16 | 0.0000 |
202859_at‡ | NM_000584 | IL-8 | −13.22 ± 0.40 | 0.0000 |
202023_at | NM_004428 | Ephrin-A1 (EFNA1) | −2.66 ± 0.15 | 0.0000 |
213624_at | AA873600 | Acid sphingomyelinase-like phosphodiesterase | −2.38 ± 0.14 | 0.0000 |
202644_at‡ | NM_006290 | Tumor necrosis factor, α-induced protein 3 (TNFAIP3) | −3.48 ± 0.18 | 0.0000 |
211343_at‡ | M33653 | Type IV collagen (COL4A2) | 4.27 ± 0.28 | 0.0000 |
203797_at‡ | AF039555 | VSNL1 | 1.58 ± 0.08 | 0.0007 |
204718_at‡ | NM_004445 | EphB6 | 2.64 ± 0.22 | 0.0022 |
207196_at | NM_006058 | Nef-associated factor 1 (NAF1) | −2.79 ± 0.23 | 0.0036 |
205205_at‡ | NM_006509 | Reticuloendotheliosis viral oncogene homolog B | −1.91 ± 0.16 | 0.0043 |
215223_at | W46388 | Mitochondrial superoxide dismutase 2 | −4.8 ± 0.40 | 0.0094 |
205067_at | NM_000576 | IL-1 | −3.92 ± 0.35 | 0.0108 |
201438_at‡ | NM_004369 | Collagen type VI, 3 (COL6A3) | 2.37 ± 0.23 | 0.0160 |
207096_at | NM_006512 | Serum amyloid A4 (SAA4) | −1.86 ± 0.17 | 0.0209 |
208378_at‡ | NM_004464 | Fibroblast growth factor 5 (FGF5) | −1.46 ± 0.11 | 0.0259 |
203381_at | N33009 | Apolipoprotein E | 3.12 ± 0.37 | 0.0532 |
213136_at | AI828880 | Protein tyrosine phosphatase, type 2 | −2.39 ± 0.28 | 0.0532 |
213807_at‡ | BE870509 | C-met protooncogene (hepatocyte growth factor receptor) | −1.58 ± 0.14 | 0.0338 |
213416_at | BG532690 | Integrin 4 (antigen CD49D) | 2.62 ± 0.31 | 0.0669 |
216663_at‡ | AC002481 | BLU | 1.79 ± 0.20 | 0.0799 |
208820_at | AL037339 | Protein tyrosine kinase 2 (PTK2) | −1.54 ± 0.14 | 0.0835 |
200636_at | NM_002840 | Protein tyrosine phosphatase, receptor type F (PTPRF) | −1.43 ± 0.14 | 0.0741 |
205534_at | NM_002589 | BH-protocadherin (brain-heart) (PCDH7) | 2.49 ± 0.29 | 0.0446 |
203582_at‡ | NM_004578 | RAS oncogene family (RAB4) | −1.36 ± 0.12 | 0.1710 |
Multiplied by 100.
The gene has been confirmed by real-time RT-PCR, ELISA, or Western blot.