TABLE 3.
MICs and MFCs for uncommon molds in three laboratories with standard RPMIa
| Species (no. tested) | Parameter | Range for antifungal agent
|
||||
|---|---|---|---|---|---|---|
| A | I | P | R | V | ||
| A. nidulans (5) | MIC | 0.2-2 | 0.06-0.2 | 0.03-2 | 0.12-2 | 0.12-2 |
| MFC | 0.5->8 | 0.06-8 | 0.03-8 | 0.12->8 | 0.12->8 | |
| A. terreus (3) | MIC | 0.5-2 | 0.06-0.2 | 0.03-0.12 | 0.5-2 | 0.5-1 |
| MFC | 1-8 | 0.2-8 | 0.12-1 | 2-8 | 1-8 | |
| Bipolaris spp. (6) | MIC | 0.06-4 | 0.03->8 | >0.007-8 | 0.2->8 | 0.12->8 |
| MFC | 0.12-8 | 0.06->8 | 0.03->8 | 1->8 | 0.2->8 | |
| C. bantiana (3)∗ | MIC | 0.12-1 | <0.007-0.5 | <0.007-0.06 | 0.2-1 | 0.12-0.5 |
| MFC | 0.12-2 | 0.03-0.5 | 0.03-1 | 0.06-4 | 0.01-2 | |
| D. constricta (3)∗ | MIC | 0.06-0.5 | 0.12-1 | 0.03-0.12 | 8->8 | 0.5-2 |
| MFC | 0.06-2 | 0.12->8 | 0.03->8 | 4->8 | 0.12->8 | |
| F. solani (3) | MIC | 0.12-4 | >8 | >8 | >8 | 4->8 |
| MFC | 0.5-4 | ND | ND | ND | 8->8 | |
| P. lilacinus (3) | MIC | >8 | 1->8 | 0.12-0.5 | 0.2-2 | 0.2-1 |
| MFC | ND | 0.2->8 | 0.2->8 | 1->8 | 0.12->8 | |
| S. prolificans (3) | MIC | 2->8 | >8 | 0.5->8 | 8->8 | 0.5->8 |
| MFC | 8->8 | ND | >8 | >8 | 1->8 | |
| T. longibrachiatum (3) | MIC | 0.5-2 | >8 | >8 | >8 | 2 |
| MFC | 1->8 | ND | ND | ND | 2->8 | |
| W. dermatitidis (3) | MIC | 0.12-0.5 | 0.12-1 | <0.007-1 | 1-8 | 0.12-0.5 |
| MFC | 0.2-1 | 0.2-1 | 0.03-8 | 1->8 | 0.12-8 | |
a
Asterisk, 72-h MICs-0 for these species; 48-h MICs-0 for other species. A, amphotericin B; I, itraconazole; P, posaconazole; R, ravuconazole; V, voriconazole. ND, no data.