Table 3. Results of generalized estimating equation models for psychosocial adjustment and scores of psychosocial adjustment and secondary outcomes in 2 groups of young- and middle-aged patients with breast cancer (N=70).

Variable and time	Control group (n=35)	Intervention group (n=35)	Crude model						Adjusted model
			Group effect		Time effect		Interaction effect		Group effect		Time effect		Interaction effect
			Wald χ² (df)	P value	Wald χ² (df)	P value	Wald χ² (df)	P value	Wald χ² (df)	P value	Wald χ² (df)	P value	Wald χ² (df)	P value
Psychosocial adjustment, mean (SD)			6.83 (1)	.009	41.03 (3)	<.001	19.03 (3)	<.001	3.62 (1)	.06	48.15 (3)	<.001	18.39 (3)	<.001
T0	46.60 (17.14)	43.86 (18.69)
T1	52.91 (18.65)	48.03 (18.13)
T2	55.32 (16.36)	43.31 (14.67)
T3	52.64 (17.47)	42.44 (17.55)
Health orientation, mean (SD)			8.41 (1)	.004	3.82 (3)	.28	477.87 (3)	<.001	7.09 (1)	.008	4.73 (3)	.19	248.08 (3)	<.001
T0	9.03 (3.20)	8.86 (2.93)
T1	9.82 (2.89)	8.40 (2.66)
T2	9.65 (2.46)	9.13 (2.85)
T3	9.14 (2.77)	9.11 (2.97)
Vocational environment, mean (SD)			7.47 (1)	.006	23.91 (3)	0	5.60 (3)	.13	4.49 (1)	.03	19.68 (3)	<.001	5.43 (3)	.14
T0	7.11 (3.11)	6.00 (3.19)
T1	8.73 (3.57)	7.43 (3.90)
T2	8.81 (2.88)	6.41 (3.40)
T3	7.68 (3.43)	6.07 (3.74)
Domestic environment, mean (SD)			5.40 (1)	.02	10.38 (3)	.02	24.30 (3)	<.001	2.01 (1)	.16	10.42 (3)	.02	29.67 (3)	<.001
T0	6.03 (3.22)	5.09 (2.97)
T1	6.12 (3.51)	6.49 (3.53)
T2	7.19 (3.98)	5.44 (2.77)
T3	7.07 (3.85)	5.07 (3.41)
Sexual relationship, mean (SD)			0.48 (1)	.49	67.19 (3)	<.001	12.36 (3)	.006	0.21 (1)	.65	64.38 (3)	<.001	12.140 (3)	.007
T0	6.00 (2.77)	6.66 (3.47)
T1	7.64 (3.44)	8.00 (3.24)
T2	8.65 (3.23)	6.97 (2.95)
T3	8.11 (3.06)	6.74 (3.10)
Expand family relationships, mean (SD)			10.63 (1)	.001	29.16 (3)	<.001	8.99 (3)	.03	8.06 (1)	.005	29.48 (3)	<.001	7.50 (3)	.06
T0	2.77 (2.38)	2.11 (1.92)
T1	3.52 (2.35)	2.49 (1.96)
T2	3.42 (2.69)	2.31 (1.87)
T3	3.96 (2.66)	2.48 (1.99)
Social environment, mean (SD)			5.24 (1)	.02	3.28 (3)	.35	11.99 (3)	.007	1.82 (1)	.18	3.61 (3)	.31	11.50 (3)	.009
T0	7.46 (4.58)	6.57 (5.26)
T1	8.21 (3.88)	7.40 (4.43)
T2	8.81 (3.19)	6.69 (4.19)
T3	8.57 (3.86)	6.78 (4.49)
Psychological distress, mean (SD)			1.43 (1)	.23	10.65 (3)	.01	41.20 (3)	<.001	0.87 (1)	.35	10.99 (3)	.01	40.41 (3)	<.001
T0	8.20 (4.68)	8.57 (4.86)
T1	8.88 (5.15)	7.83 (4.88)
T2	8.81 (4.21)	6.38 (4.08)
T3	8.11 (4.45)	6.19 (4.45)
Self-efficacy, mean (SD)			2.57 (1)	.11	10.93 (3)	.01	2.42 (3)	.49	0.05 (1)	.83	12.35 (3)	.006	2.86 (3)	.42
T0	25.94 (6.87)	27.17 (7.06)
T1	27.00 (6.72)	27.23 (6.66)
T2	24.84 (7.19)	26.47 (6.68)
T3	25.14 (7.24)	26.41 (6.58)
Social support, mean (SD)			2.84 (1)	.09	3.95 (3)	.27	94.25 (3)	<.001	5.11 (1)	.02	3.59 (3)	.31	101.90 (3)	<.001
T0	43.77 (7.38)	44.66 (7.15)
T1	43.55 (8.05)	45.40 (7.73)
T2	41.48 (7.82)	45.81 (6.68)
T3	43.46 (7.39)	46.00 (7.12)
Coping mode to confrontation, mean (SD)			3.44 (1)	.06	1.34 (3)	.72	29.77 (3)	<.001	2.47 (1)	.12	1.64 (3)	.65	28.29 (3)	<.001
T0	20.20 (2.77)	20.20 (3.45)
T1	20.36 (2.86)	20.66 (3.13)
T2	19.87 (3.30)	21.34 (3.42)
T3	19.68 (3.07)	21.37 (3.59)
Coping mode to avoidance, mean (SD)			2.05 (1)	.15	85.93 (3)	<.001	18.72 (3)	<.001	2.05 (1)	.15	85.93 (3)	0	18.72 (3)	<.001
T0	16.49 (2.36)	18.37 (2.76)
T1	17.88 (2.03)	18.06 (2.59)
T2	17.26 (3.04)	16.91 (2.74)
T3	17.32 (2.18)	17.41 (2.90)
Coping mode to acceptance to resignation, mean (SD)			2.94 (1)	.09	5.417 (3)	.14	17.55 (3)	.001	1.37 (1)	.24	6.68 (3)	.08	12.46 (3)	.006
T0	8.23 (2.28)	8.09 (2.87)
T1	8.33 (2.87)	7.66 (2.61)
T2	8.55 (2.53)	7.63 (2.41)
T3	8.86 (3.10)	7.63 (3.13)