TABLE 2.
Results of cross-infection experiments with P. carinii
| Pneumocystis origin | Group no. | Recipient host | Cyst count (106) | Total parasites (106) | PCPa | Positive PCRa | P. carinii f. sp. murisa, b | P. carinii f. sp. hominisa, b |
|---|---|---|---|---|---|---|---|---|
| Human | 1 to 5 | SCID mouse | 0 | 0 | 0/15 | 0/15 | 0/15 | 0/15 |
| Mouse | 6 | SCID mouse | 0.9 ± 0.4 | 20.9 ± 5.1 | 3/3 | 3/3 | 3/3 | 0/3 |
| Mouse | 7 | SCID mouse | 2.3 ± 0.2 | 85.5 ± 30.3 | 3/3 | 3/3 | 3/3 | 0/3 |
| Control SCID mice | 8 | 0 | 0 | 0/5 | 0/5 | 0/5 | 0/5 |
a
Number of positive results per total number of examined SCID mice.
b
P. carinii f. sp. muris and P. carinii f. sp. hominis were identified with oligonucleotidic-specific probes by hybridization.