TABLE 3.
Risk factors associated with clustering in Ethiopian patients with pulmonary TB by multivariate regression analysis
| Variable | All patients
|
Addis Ababa residents
|
||||||
|---|---|---|---|---|---|---|---|---|
| Clustered (n = 51) | Nonclustered (n = 70) | Adjusted ORa (95% CI) | P value | Clustered (n = 37) | Nonclustered (n = 54) | Adjusted ORb (95% CI) | P value | |
| Mean age (yr [median; range]) | 29.3 (29.0;16-50) | 31.1 (28.0;15-62) | 3.69 (0.61-25.48) | 0.17 | 29.7 (30;17-50) | 31.2 (29;15-65) | 2.43 (0.25-27.51) | 0.45 |
| Sex (no. [%] of patients) | ||||||||
| Male | 30 (58.8) | 48 (68.6) | 19 (51.4) | 38 (70.4) | 1.00 | 0.11 | ||
| Female | 21 (41.2) | 22 (31.4) | 18 (48.7) | 16 (29.6) | 2.10 (0.85-5.25) | |||
| No. (%) of patients with: | ||||||||
| Residence in Addis Ababa | 40 (78.4) | 51 (72.9) | ||||||
| Previous TB treatment | 8 (15.7) | 10 (14.3) | 5 (13.5) | 7 (13.0) | ||||
| Isolate resistance with (any drug) | 7 (13.2) | 10 (14.7) | 7 (16.7) | 7 (14.3) | ||||
| Positive for AFB by direct exam- ination of a sputum smear | 28 (54.9) | 39 (55.7) | 19 (51.4) | 29 (53.7) | ||||
| Cavitary TB | 16 (31.4) | 32 (32.9) | 11 (29.7) | 17 (31.5) | ||||
| HIV status (no. [%] of patients) | ||||||||
| Positive | 37 (70.6) | 36 (51.4) | 2.55 (1.17-5.80) | 0.021 | 28 (75.7) | 32 (59.3) | 2.33 (0.90-6.45) | 0.088 |
| Negative | 15 (29.4) | 34 (48.6) | 1.00 | 9 (24.3) | 22 (40.7) | 1.00 | ||
a
The final model includes age and HIV infection status. The remaining variables are not significant in the multivariate model.\
b
The final model includes age, sex, and HIV infection status. The remaining variables are not significant in the multivariate model.